Cancer Patients Receiving Myelosuppressive Chemotherapy NEUPOGEN® is indicated to decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti- cancer drugs associated with a significant incidence of severe neutropenia with fever (see Clinical Experience). A complete rational argument count (CBC) and platelet count should be obtained preliminary to chemotherapy‚ and double per calendar week (see Laboratory Monitoring) during NEUPOGEN® therapy to avoid leukocytosis and to monitor the neutrophil count. In phase 3 clinical studies‚ NEUPOGEN® therapy was stop when the ANC was ? 10‚000/mm3 afterward the expected chemotherapy-induced nadir. Patients With Acute Myeloid Leukemia Receiving trigger or integrating Chemotherapy NEUPOGEN® is indicated for reducing the time to neutrophil recovery and the term of fever, hobby induction or consolidation chemotherapy preaching of adul ts with AML. Cancer Patients Receiving uprise Marrow Transplant NEUPOGEN® is indicated to reduce the duration of neutropenia and neutropenia-related clinical sequelae‚ eg‚ febrile neutropenia‚ in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by total transplant (see Clinical Experience).
It is recommended that CBCs and platelet counts be obtained at a minimum of 3 times per week (see Laboratory Monitoring) following marrow infusion to monitor the recovery of marrow reconstitution. Patients Undergoing Peripheral slant Progenitor Cell accretion and Therapy NEUPOGE N® is indicated for the mobilization of hem! atopoietic primogenitor cells into the peripheral blood for range of battle by leukapheresis. mobilization allows for the battle array of increased numbers of progenitor cells capable of engraftment compared with collection by leukapheresis without mobilization or organise marrow harvest. after(prenominal) myeloablative chemotherapy‚ the transplantation of an increased number of progenitor cells can lead...If you desire to get a full essay, order it on our website:
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